Crossing genitourinary limits: First case of monkeypox diagnosed by a urology service in Mexico. A diagnostic challenge.

This case is the first documented instance of genitourinary monkeypox (Mpox) diagnosed by a urology service in Mexico, emphasizing the role of urologists in managing atypical genitourinary infections. A 28-year-old homosexual male with HIV developed penile swelling and pustular lesions, confirmed as MPXV infection by PCR. Symptomatic management was initiated, and the patient was referred for tecovirimat therapy under a clinical trial. Mpox lesions often mimic sexually transmitted conditions, leading to diagnostic delays. Limited awareness among healthcare providers compounds these challenges. Urologists must consider Mpox in atypical genital cases, particularly in high-risk populations, to ensure timely diagnosis and treatment.