Scientific reports · 2024
Screening great ape museum specimens for DNA viruses.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Hämmerle Michelle, Guellil Meriam, Trgovec-Greif Lovro, Cheronet Olivia, Sawyer Susanna, Ruiz-Gartzia Irune, Lizano Esther, Rymbekova Aigerim, Gelabert Pere, Bernardi Paolo, Han Sojung, Rattei Thomas, Schuenemann Verena J, Marques-Bonet Tomas, Guschanski Katerina, Calvignac-Spencer Sebastien, Pinhasi Ron, Kuhlwilm Martin
Аннотация
Natural history museum collections harbour a record of wild species from the past centuries, providing a unique opportunity to study animals as well as their infectious agents. Thousands of great ape specimens are kept in these collections, and could become an important resource for studying the evolution of DNA viruses. Their genetic material is likely to be preserved in dry museum specimens, as reported previously for monkeypox virus genomes from historical orangutan specimens. Here, we screened 209 great ape museum specimens for 99 different DNA viruses, using hybridization capture coupled with short-read high-throughput sequencing. We determined the presence of multiple viruses within this dataset from historical specimens and obtained several near-complete viral genomes. In particular, we report high-coverage (> 18-fold) hepatitis B virus genomes from one gorilla and two chimpanzee individuals, which are phylogenetically placed within clades infecting the respective host species.