The post-acute phase of new-onset refractory status epilepticus (NORSE) / febrile infection-related epilepsy syndrome (FIRES).

In this narrative review, we will summarize the existing literature describing long-term outcomes after new-onset refractory status epilepticus and febrile infection-related epilepsy syndrome. Febrile infection-related epilepsy syndrome is more common in children and has been described as a multiphasic presentation with a prodrome, an acute epileptic phase and a chronic epileptic phase. Important long-term sequelae after resolution of the acute phase of new-onset refractory status epilepticus and febrile infection-related epilepsy syndrome include survival and mortality, seizures, cognition and functioning, mental health and behavioral changes, general medical sequelae, quality of life and the enormous impact of these outcomes on caregivers and families.