Personalized drug discovery from rare diseases to cancer.

Precision medicine selects individual treatments from a small toolbox of therapies already available. Personalized drug discovery (PDD) brings this concept one step ahead, developing drugs for individual patient's diseases. Currently, PDD is being developed for rare disorders, where conventional drug discovery paradigms are non-applicable due to small patient sizes, but also for cancer. As a new frontier in precision medicine, PDD should be upscaled in rare and non-rare diseases.