Emerging infectious diseases · 2023
Comprehensive Case-Control Study of Protective and Risk Factors for Buruli Ulcer, Southeastern Australia.
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
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McNamara Bridgette J, Blasdell Kim R, Yerramilli Arvind, Smith Ina L, Clayton Simone L, Dunn Michael, Tay Ee Laine, Gibney Katherine B, Waidyatillake Nilakshi T, Hussain Mohammad A, Muleme Michael, O'Brien Daniel P, Athan Eugene
Аннотация
To examine protective and risk factors for Buruli ulcer (BU), we conducted a case-control study of 245 adult BU cases and 481 postcode-matched controls across BU-endemic areas of Victoria, Australia. We calculated age- and sex-adjusted odds ratios for socio-environmental, host, and behavioral factors associated with BU by using conditional logistic regression. Odds of BU were >2-fold for persons with diabetes mellitus and persons working outdoors who had soil contact in BU-endemic areas (compared with indoor work) but were lower among persons who had bacillus Calmette-Guérin vaccinations. BU was associated with increasing numbers of possums and with ponds and bore water use at residences. Using insect repellent, covering arms and legs outdoors, and immediately washing wounds were protective; undertaking multiple protective behaviors was associated with the lowest odds of BU. Skin hygiene/protection behaviors and previous bacillus Calmette-Guérin vaccination might provide protection against BU in BU-endemic areas.