[Precise diagnosis of allergic diseases: construction of a clinical decision-making system based on epidemiology and quantitative IgE testing].

Allergen-specific IgE testing plays a critical role in the diagnosis and management of allergic diseases. Compared with traditional methods, quantitative IgE testing offers more precise diagnostic support, facilitates assessment of disease severity, guides personalized treatment, and improves the prediction of disease onset and prognosis. Given China's vast territory and regional diversity in geography, climate, dietary habits, and age distribution, the spectrum and prevalence of allergens vary significantly across populations. Therefore, the selection of allergens for testing should be guided by patients' clinical histories and regional epidemiological characteristics. Broad, non-targeted screening may lead to misinterpretation of allergen sensitization results. This article integrates epidemiological data and age stratification with quantitative allergen-specific IgE testing to standardize allergen testing practices and promote precision diagnosis and treatment of allergic diseases.