Mild/Moderate Asthma Network in Italy (MANI): a long-term observational study.
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Braido Fulvio, Blasi Francesco, Canonica Giorgio Walter, Paggiaro Pierluigi, Beghè Bianca, Bonini Matteo, Carpagnano Giovanna Elisiana, Del Giacco Stefano, Lavorini Federico, Milanese Manlio, Patella Vincenzo, Santus Pierachille, Contoli Marco, MANI Network, Allegrini Chiara, Baiardini Ilaria, Bonzano Laura, Caiaffa Maria Filomena, Castelnuovo Paolo, Corsico Angelo Guido, Cosmi Lorenzo, Costantino Maria Teresa, Cottini Marcello, Crimi Nunzio, Crivellaro Maria Angiola, D'Alò Simona, Folletti Ilenia, Fornari Dario, Foschino-Barbaro Maria Pia, Franceschini Laura, Gargano Domenico, Oliani Kim Lokar, Maniscalco Mauro, Melissari Laura, Montagni Marcello, Montuschi Paolo, Murgia Nicola, Pannofino Alessandro, Papi Alberto, Parente Roberta, Pelaia Girolamo, Pini Laura, Puggioni Francesca, Pulerà Nolita, Resta Onofrio, Ricciardi Luisa, Ridolo Erminia, Savi Eleonora, Savoia Francesca, Scala Guglielmo, Senna Gianenrico, Tripodi Salvatore, Vatrella Alessandro, Ventura Maria Teresa, Viviano Vittorio Maria, Yacoub Mona-Rita
Аннотация
METHODS: This study, called the Mild/Moderate Asthma Network of Italy (MANI), is a research initiative launched by the Italian Respiratory Society and the Italian Society of Allergology, Asthma and Clinical Immunology. MANI is a cluster-based, real world, cross-sectional, prospective, observational cohort study that includes 20,000 patients with mild-to-moderate asthma. (ClinicalTrials.gov Identifier: NCT04796844).
RESULTS AND CONCLUSION: Despite advances in asthma care, several research gaps remain to be addressed through clinical research. This study will add important new knowledge about long-term disease history, the transferability of clinical research results to daily practice, the efficacy of currently recommended strategies, and their impact on the burden and evolution of the disease.
ABBREVIATIONS: MANI:Mild/Moderate Asthma Network of ItalySANI:Severe Asthma Network ItalyGINA:Global Initiative for AsthmaSABA:short acting β2-agonistsICS:inhaled corticosteroidsCRF:Case Report Form.