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Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2021

COVID-19 in the tonsillectomised population.

СтатьяНаблюдательное исследованиеНазвание и аннотация: Перевод в очереди
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Capriotti Vincenzo, Mattioli Francesco, Guida Francesco, Marcuzzo Alberto Vito, Lo Manto Alfredo, Martone Andrea, Molinari Giulia, Fabbris Cristoforo, Menegaldo Anna, Calvanese Leonardo, Latini Gino, Cingolani Cristina, Gradoni Paolo, Boscolo Nata Francesca, De Sisti Clelia, Selle Vittorio, Leone Giordano, Indelicato Pietro, Pilolli Francesco, Mevio Niccolò, Roncoroni Luca, Papi Simona, Meschiari Marianna, Tominz Riccardo, D'Ascanio Luca, Dragonetti Alberto, Torelli Lucio, Trenti Loris, Spinato Giacomo, Boscolo-Rizzo Paolo, Bussi Mario, Cossarizza Andrea, Presutti Livio, Tirelli Giancarlo

Аннотация

OBJECTIVE: Interactions between SARS-CoV-2 and pharyngeal associated lymphoid tissue are thought to influence the manifestations of COVID-19. We aimed to determine whether a previous history of tonsillectomy, as a surrogate indicator of a dysfunctional pharyngeal associated lymphoid tissue, could predict the presentation and course of COVID-19.

METHODS: Multicentric cross-sectional observational study involving seven hospitals in Northern and Central Italy. Data on the clinical course and signs and symptoms of the infection were collected from 779 adults who tested positive for SARS-CoV-2, and analysed in relation to previous tonsillectomy, together with demographic and anamnestic data.

RESULTS: Patients with previous tonsillectomy showed a greater risk of fever, temperature higher than 39°C, chills and malaise. No significant differences in hospital admissions were found.

CONCLUSIONS: A previous history of tonsillectomy, as a surrogate indicator of immunological dysfunction of the pharyngeal associated lymphoid tissue, could predict a more intense systemic manifestation of COVID-19. These results could provide a simple clinical marker to discriminate suspected carriers and to delineate more precise prognostic models.

Предметные рубрики MeSH

ИП Урсолов Владлен Сергеевич

ИНН 500118482352 · ОГРНИП 314500117700049

Реквизиты и контакты