Surgical infections · 2012
Chemotherapeutically induced cutaneous tuberculosis after BCG injection in a patient with pelvic osteosarcoma.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Zoccali Giovanni, Cota Carlo, Marolda Giulio, Ferraresi Virginia, Giuliani Maurizio, Zoccali Carmine
Аннотация
BACKGROUND: Tuberculosis (TB) is a serious infection afflicting a multitude of people worldwide. Recently, its prevalence has increased. The incidence of skin involvement generally is low. Bacillus Calmette-Guérin (BCG) is a live attenuated strain of Mycobacterium bovis that typically is administered as a vaccine to stimulate the immune system when treating some early neoplasms or to guard against tuberculosis.
METHODS: Case report and literature review.
CASE REPORT: The authors describe a young man with osteosarcoma of the left hemipelvis who received intradermal BCG injection for immune stimulation prior to surgery. In the course of neoadjuvant chemotherapy, he developed cutaneous tuberculosis.
CONCLUSION: It is our opinion that BCG injection should be avoided in all patients requiring surgery, especially in oncologic patients, where the immunodeficiency brought on by chemotherapy predisposes to active opportunistic infection.
METHODS: Case report and literature review.
CASE REPORT: The authors describe a young man with osteosarcoma of the left hemipelvis who received intradermal BCG injection for immune stimulation prior to surgery. In the course of neoadjuvant chemotherapy, he developed cutaneous tuberculosis.
CONCLUSION: It is our opinion that BCG injection should be avoided in all patients requiring surgery, especially in oncologic patients, where the immunodeficiency brought on by chemotherapy predisposes to active opportunistic infection.