Eye (London, England) · 2013
Retinal angiomatous proliferation occurring after radiotherapy.
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De Salvo G, Hannan S R, James N, Lotery A J
Аннотация
PURPOSE: To describe two cases of retinal angiomatous proliferation (RAP)-like lesion following radiation therapy for primary tumor.
PATIENTS AND METHODS: Retrospective evaluation of two patients with previous irradiation treatment for a pleomorphic adenoma of the lacrimal gland and a vocal cord carcinoma, respectively. Visual acuity (VA), fluorescein angiography and optical coherence tomography were performed and demonstrated a RAP-like lesion in both cases. Treatment with intravitreal injections of Ranibizumab was performed with a follow-up of 19 and 10 months, respectively.
RESULTS: Both the patients had a positive response to the treatment with improvement in VA and reduction of intraretinal fluid.
CONCLUSION: RAP-like lesions can develop following radiation treatment for a primary tumor. In patients presenting with idiopathic RAP, a history of prior radiotherapy should be considered.
PATIENTS AND METHODS: Retrospective evaluation of two patients with previous irradiation treatment for a pleomorphic adenoma of the lacrimal gland and a vocal cord carcinoma, respectively. Visual acuity (VA), fluorescein angiography and optical coherence tomography were performed and demonstrated a RAP-like lesion in both cases. Treatment with intravitreal injections of Ranibizumab was performed with a follow-up of 19 and 10 months, respectively.
RESULTS: Both the patients had a positive response to the treatment with improvement in VA and reduction of intraretinal fluid.
CONCLUSION: RAP-like lesions can develop following radiation treatment for a primary tumor. In patients presenting with idiopathic RAP, a history of prior radiotherapy should be considered.
Предметные рубрики MeSH
Adenoma, PleomorphicAged, 80 and overAngiogenesis InhibitorsAntibodies, Monoclonal, HumanizedEye NeoplasmsFemaleFluorescein AngiographyHumansLacrimal Apparatus DiseasesLaryngeal NeoplasmsMaleRadiation InjuriesRadiotherapyRanibizumabRetinaRetinal NeovascularizationRetrospective StudiesTomography, Optical CoherenceVisual AcuityVocal Cords