Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography · 2007
Safety and predictors of complications with a new accelerated dobutamine stress echocardiography protocol.
Сравнительное исследованиеСтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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San Román José Alberto, Sanz-Ruiz Ricardo, Ortega José Ramón, Pérez-Paredes Matías, Rollán María Jesús, Muñoz Ana Cristina, Segura Federico, Jimenez Diego, Carnero Andres, Pinedo Marta, Arnold Roman, Gómez Itziar, Fernández-Aviles Francisco
Аннотация
BACKGROUND: This study sought to document the safety of a new accelerated dobutamine-atropine stress echocardiography protocol and to analyze its complications.
METHODS: Dobutamine-atropine stress echocardiography studies were performed using an incremental dobutamine infusion protocol from 20 to 40 microg/kg/min in 3-minute stages and followed by atropine.
RESULTS: A total of 962 patients were included. Mean age was 64 +/- 11 years and 584 were male (61%). Mean ejection fraction was 62 +/- 10%. Complications included hypertensive responses in 66 patients (7%), arrhythmias in 26 (2.7%), and symptomatic hypotension in 16 (1.7%). No patient developed heart failure, acute myocardial infarction, ventricular fibrillation, or died. The independent predictors of hypertensive responses were age, baseline systolic blood pressure, and treatment with nitrates. The independent predictors of arrhythmias were history of hypertension, previous coronary artery disease, and baseline heart rate.
CONCLUSIONS: This accelerated dobutamine-atropine stress echocardiography protocol is safe in a low-risk population and has a rate of complications similar to that reported for the standard protocol.
METHODS: Dobutamine-atropine stress echocardiography studies were performed using an incremental dobutamine infusion protocol from 20 to 40 microg/kg/min in 3-minute stages and followed by atropine.
RESULTS: A total of 962 patients were included. Mean age was 64 +/- 11 years and 584 were male (61%). Mean ejection fraction was 62 +/- 10%. Complications included hypertensive responses in 66 patients (7%), arrhythmias in 26 (2.7%), and symptomatic hypotension in 16 (1.7%). No patient developed heart failure, acute myocardial infarction, ventricular fibrillation, or died. The independent predictors of hypertensive responses were age, baseline systolic blood pressure, and treatment with nitrates. The independent predictors of arrhythmias were history of hypertension, previous coronary artery disease, and baseline heart rate.
CONCLUSIONS: This accelerated dobutamine-atropine stress echocardiography protocol is safe in a low-risk population and has a rate of complications similar to that reported for the standard protocol.
Предметные рубрики MeSH
Adrenergic beta-AgonistsAgedArrhythmias, CardiacAtropineBlood PressureDobutamineDose-Response Relationship, DrugDrug EvaluationEchocardiographyEchocardiography, StressElectrocardiographyFemaleHeadacheHumansHypertensionHypotensionLogistic ModelsMaleMiddle AgedMuscarinic AntagonistsNauseaPredictive Value of TestsRisk AssessmentTachycardia, VentricularTime FactorsTremor