Early human development · 2004
Respiratory characteristics of infants with pulmonary hypoplasia syndrome following preterm rupture of membranes: a preliminary study for establishing clinical diagnostic criteria.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Suzuki Keiji
Аннотация
BACKGROUND: At present, the diagnosis of pulmonary hypoplasia is based on postmortem findings, and there are no clear clinical diagnostic criteria to facilitate its identification and management.
AIM: To characterise the respiratory status of pulmonary hypoplasia syndrome (PHS) following preterm rupture of membranes so as to establish its clinical diagnostic criteria.
STUDY DESIGN: Retrospective comparison of respiratory characteristics of six typical PHS infants with six wet lung syndrome (WLS) infants who served as controls.
SUBJECTS: The PHS and WLS infants were selected from 1094 patients admitted to a tertiary care neonatal unit over a 6-year period, with criteria based on perinatal history, respiratory signs, X-ray and laboratory findings, and ventilator settings.
OUTCOME MEASURES: The compared variables were lung volume index (LVI) calculated from lung dimensions on chest X-ray, ventilatory index (VI), ventilatory efficiency index (VEI), response to artificial surfactant treatment, and ventilation days.
RESULTS: In PHS compared to WLS infants, LVI was lower (4.5 +/- 0.5 vs. 9.5 +/- 1.5; p < 0.01), VI was higher (0.108 +/- 0.030 vs. 0.022 +/- 0.005; p < 0.05), and VEI was lower (0.083 +/- 0.012 vs. 0.258 +/- 0.052; p < 0.01) (mean +/- S.E.). Artificial surfactant was given to four PHS infants, but none of them showed respiratory improvement. Ventilation days were 11-79 in three surviving PHS infants and 2-14 in WLS infants.
CONCLUSIONS: In this preliminary study, low LVI (< 6.5) and VEI (< 0.15) were the most useful indicators of PHS.
AIM: To characterise the respiratory status of pulmonary hypoplasia syndrome (PHS) following preterm rupture of membranes so as to establish its clinical diagnostic criteria.
STUDY DESIGN: Retrospective comparison of respiratory characteristics of six typical PHS infants with six wet lung syndrome (WLS) infants who served as controls.
SUBJECTS: The PHS and WLS infants were selected from 1094 patients admitted to a tertiary care neonatal unit over a 6-year period, with criteria based on perinatal history, respiratory signs, X-ray and laboratory findings, and ventilator settings.
OUTCOME MEASURES: The compared variables were lung volume index (LVI) calculated from lung dimensions on chest X-ray, ventilatory index (VI), ventilatory efficiency index (VEI), response to artificial surfactant treatment, and ventilation days.
RESULTS: In PHS compared to WLS infants, LVI was lower (4.5 +/- 0.5 vs. 9.5 +/- 1.5; p < 0.01), VI was higher (0.108 +/- 0.030 vs. 0.022 +/- 0.005; p < 0.05), and VEI was lower (0.083 +/- 0.012 vs. 0.258 +/- 0.052; p < 0.01) (mean +/- S.E.). Artificial surfactant was given to four PHS infants, but none of them showed respiratory improvement. Ventilation days were 11-79 in three surviving PHS infants and 2-14 in WLS infants.
CONCLUSIONS: In this preliminary study, low LVI (< 6.5) and VEI (< 0.15) were the most useful indicators of PHS.