Neurology India · 2025
Non-Motor Symptoms in Parkinson's Disease and Their Impact on Quality of Life: A Cross-Sectional Study.
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Ahsan Suhail, Mehta Sahil, Chakravarti Kamalesh, Ray Sucharita, Grover Sandeep, Saharan Rajveer, Lal Vivek
Аннотация
BACKGROUND: Non-motor symptoms have a more significant impact on the quality of life in Parkinson's disease than motor symptoms.
OBJECTIVES: To evaluate the frequency of non-motor symptoms in Parkinson's disease and study their impact on quality of life.
METHODS: A cross-sectional study was conducted on 100 patients with idiopathic Parkinson's disease. All patients underwent a detailed history and neurological examination, Hoehn and Yahr staging, MDS UPDRS scoring, NMSS scoring, and PDQ-39 scoring to assess their quality of life.
RESULTS: All patients presented with at least one non-motor symptom. The most frequently affected non-motor symptom was sleep/fatigue (95%), followed by urinary (79%) and gastrointestinal dysfunction (76%). The total NMSS score significantly correlated with disease severity and quality of life.
CONCLUSION: Non-motor symptoms are quite prevalent in patients with Parkinson's disease and significantly impact their quality of life.
OBJECTIVES: To evaluate the frequency of non-motor symptoms in Parkinson's disease and study their impact on quality of life.
METHODS: A cross-sectional study was conducted on 100 patients with idiopathic Parkinson's disease. All patients underwent a detailed history and neurological examination, Hoehn and Yahr staging, MDS UPDRS scoring, NMSS scoring, and PDQ-39 scoring to assess their quality of life.
RESULTS: All patients presented with at least one non-motor symptom. The most frequently affected non-motor symptom was sleep/fatigue (95%), followed by urinary (79%) and gastrointestinal dysfunction (76%). The total NMSS score significantly correlated with disease severity and quality of life.
CONCLUSION: Non-motor symptoms are quite prevalent in patients with Parkinson's disease and significantly impact their quality of life.