Journal of the American Academy of Dermatology · 1997
PUVA-induced phototoxicity: incidence and causes.
СтатьяНазвание и аннотация: Перевод в очереди
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Morison W L, Marwaha S, Beck L
Аннотация
BACKGROUND: Phototoxicity is the most significant short-term adverse effect of PUVA therapy.
OBJECTIVE: We attempted to determine the incidence and possible causes of phototoxicity of sufficient degree to cause interruption of treatment.
METHODS: A retrospective study was conducted of 16,506 PUVA treatments given to 414 patients in two treatment centers.
RESULTS: Phototoxicity occurred in 10.9% of patients and was an adverse effect in 0.3% of treatments. Problems with the treatment protocol were the main cause.
CONCLUSION: Phototoxicity is a common adverse effect, and patients should be warned of this potential occurrence. Awareness of the causes may help to reduce the incidence of this problem.
OBJECTIVE: We attempted to determine the incidence and possible causes of phototoxicity of sufficient degree to cause interruption of treatment.
METHODS: A retrospective study was conducted of 16,506 PUVA treatments given to 414 patients in two treatment centers.
RESULTS: Phototoxicity occurred in 10.9% of patients and was an adverse effect in 0.3% of treatments. Problems with the treatment protocol were the main cause.
CONCLUSION: Phototoxicity is a common adverse effect, and patients should be warned of this potential occurrence. Awareness of the causes may help to reduce the incidence of this problem.