Human vaccines & immunotherapeutics · 2022
Breakthrough SARS-CoV-2 infections after vaccination: a critical review.
СтатьяОбзорНазвание и аннотация: Перевод в очереди
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Mohseni Afshar Zeinab, Barary Mohammad, Hosseinzadeh Rezvan, Alijanpour Amirmasoud, Hosseinzadeh Dariush, Ebrahimpour Soheil, Nazary Kosar, Sio Terence T, Sullman Mark J M, Carson-Chahhoud Kristin, Babazadeh Arefeh
Аннотация
At the beginning of the current pandemic, it was believed that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection would induce lifelong immunity and that reinfections would be unlikely. However, after several cases of reinfection were documented in previously infected patients, this was understood to be a false assumption, and this waning humoral immunity has raised significant concerns. Accordingly, long-term and durable vaccine-induced antibody protection against infection have also become a challenge, as several breakthroughs of COVID-19 infection have been identified in individuals who were fully vaccinated. This review discusses the current evidence on breakthrough COVID-19 infections occurring after vaccination.