Two probable cases of treponemal disease of Medieval date from England.

Two British Medieval skeletons are described. Paleopathological examination suggests that treponemal disease was present in each case. Radiocarbon dating indicates that one is firmly pre-Columbian, and the other of likely pre-Columbian date. The implications for our understanding of the history and geographic spread of the treponemal diseases, particularly venereal syphilis, are discussed.