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DOI 10.1016/j.cmpb.2024.108358

Медицинская библиотека · Computer methods and programs in biomedicine · 2024

Improved rank-based recursive feature elimination method based ovarian cancer detection model via customized deep architecture.

Rani Namani Deepika, Babu Mahesh

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Аннотация

BACKGROUND

Ovarian cancer is often considered the most lethal gynecological cancer because it tends to be diagnosed at an advanced stage, leading to limited treatment options and poorer outcomes. Several factors contribute to the challenges in managing ovarian cancer, namely rapid metastasis, genetic factors, reproductive history, etc. This necessitates the prompt and precise diagnosis of ovarian cancer in order to carry out efficient treatment plans and give patients who are all impacted by OC the care and support they need.

METHODS

This CCLSTM model is suggested under four essential stages including preprocessing, feature extraction, feature selection and detection. Initially, the input data is preprocessed using Improved Two-step Data Normalization. Subsequently, features such as statistical, modified entropy, raw features and mutual information are extracted from the normalized data. Next, obtained features undergo the Improved Rank-based Recursive Feature Elimination method (IR-RFE) to select the most suitable features. Finally, the proposed CCLSTM model takes the selected features as input and provides a final detection outcome.

RESULTS

Furthermore, the performance of the proposed CCLSTM technique is examined through a thorough assessment using diverse analyses Additionally, the CCLSTM schemes show a sensitivity value of 0.948, whereas the sensitivity ratings for ALO-LSTM + ALOCNN, Bi-GRU, LSTM, RNN, KNN, CNN, and DCNN are 0.808, 0.893, 0.829, 0.851, 0.765, 0.872, and 0.893, respectively.

CONCLUSION

In the end, the development of CNN and the addition of LSTM technique have produced an ovarian cancer detection technique that is more accurate and consistent compared to other existing strategies.

Для цитирования: Rani Namani Deepika, Babu Mahesh. Improved rank-based recursive feature elimination method based ovarian cancer detection model via customized deep architecture.. Computer methods and programs in biomedicine. 2024. DOI: 10.1016/j.cmpb.2024.108358.

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