Emerging infectious diseases · 2023
Prevalence of Undiagnosed Monkeypox Virus Infections during Global Mpox Outbreak, United States, June-September 2022.
СтатьяНазвание и аннотация: Перевод в очереди
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Minhaj Faisal S, Singh Vijay, Cohen Stephanie E, Townsend Michael B, Scott Hyman, Szumowski John, Hare C Bradley, Upadhyay Pallavi, Reddy Jairus, Alexander Barbara, Baird Nicolle, Navarra Terese, Priyamvada Lalita, Wynn Nhien, Carson William C, Odafe Solomon, Guagliardo Sarah Anne J, Sims Emily, Rao Agam K, Satheshkumar Panayampalli S, Weidle Paul J, Hutson Christina L
Аннотация
Since May 2022, mpox has been identified in 108 countries without endemic disease; most cases have been in gay, bisexual, or other men who have sex with men. To determine number of missed cases, we conducted 2 studies during June-September 2022: a prospective serologic survey detecting orthopoxvirus antibodies among men who have sex with men in San Francisco, California, and a retrospective monkeypox virus PCR testing of swab specimens submitted for other infectious disease testing among all patients across the United States. The serosurvey of 225 participants (median age 34 years) detected 18 (8.0%) who were orthopoxvirus IgG positive and 3 (1.3%) who were also orthopoxvirus IgM positive. The retrospective PCR study of 1,196 patients (median age 30 years; 54.8% male) detected 67 (5.6%) specimens positive for monkeypox virus. There are likely few undiagnosed cases of mpox in regions where sexual healthcare is accessible and patient and clinician awareness about mpox is increased.