Purtscher-like retinopathy related to drug-induced hypersensitivity syndrome.

PURPOSE: To report a case with Purtscher-like retinopathy related to drug-induced hypersensitivity syndrome (DIHS).

DESIGN

Case report.

METHODS

A 31-year-old male with fever, macula-papular rash, lymphadenopathy, and hepatitis was hospitalized.

RESULTS

Eosinophilic leukocytosis, as well as cotton wool spots around the optic disc, was observed. Viral, bacteriologic, and parasitologic tests and rheumatologic markers were all negative. Given his history of antibiotic use, he was diagnosed as DIHS. On the seventh day he lost consciousness and and on the tenth day he died.

CONCLUSION

Purtscher-like retinopathy might be a sign of DIHS, and should be considered in the differential diagnosis where early intervention is needed.