Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 2025
Retrospective Review of the Infection Rate of Lower Extremities Treated With Mohs Micrographic Surgery With and Without Prophylactic Antibiotics.
СтатьяНазвание и аннотация: Перевод в очереди
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Patel Jay R, Gimenez Mariana Chrispim, Shamloul Norhan, Brown Marc D, Smith Franki Lambert
Аннотация
BACKGROUND: Prophylactic antibiotic use in Mohs micrographic surgery (MMS) is guided by descriptive studies in the 2008 advisory statement recommending use for high-risk sites, including lower extremities due to a greater than 5% infection rate. Studies since 2008 have not identified decreases in infection with prophylactic antibiotics.
OBJECTIVE: To identify the impact of preoperative prophylactic antibiotics on lower extremity infection rate for patients undergoing MMS.
METHODS: A retrospective review was conducted at the University of Rochester Department of Dermatology from one surgeon (1/2019-6/2024). Adults undergoing MMS to below the knee were included. Patients from 2019 to 2021 had routine preoperative dose of 1 g oral cefadroxil. Patients from 2022 to 2024 did not receive preoperative antibiotics. Patient demographics, tumor type, surgery characteristics, reconstruction, prophylactic antibiotic use, and infection were collected. Chi squared analysis and the Mann-Whitney test compared complications.
RESULTS: Of 178 cases, prophylactic antibiotics were used in 45.5% (81/178). The prophylactic antibiotic group had an infection rate of 11.1% (9/81) versus 8.3% (8/97) in patients not receiving antibiotics, p = .52. Demographic, tumor, or surgical characteristics were not associated with an increased infection rate, p > .05.
CONCLUSION: There is no decrease in infection rate of below the knee MMS with preoperative prophylactic antibiotics.
OBJECTIVE: To identify the impact of preoperative prophylactic antibiotics on lower extremity infection rate for patients undergoing MMS.
METHODS: A retrospective review was conducted at the University of Rochester Department of Dermatology from one surgeon (1/2019-6/2024). Adults undergoing MMS to below the knee were included. Patients from 2019 to 2021 had routine preoperative dose of 1 g oral cefadroxil. Patients from 2022 to 2024 did not receive preoperative antibiotics. Patient demographics, tumor type, surgery characteristics, reconstruction, prophylactic antibiotic use, and infection were collected. Chi squared analysis and the Mann-Whitney test compared complications.
RESULTS: Of 178 cases, prophylactic antibiotics were used in 45.5% (81/178). The prophylactic antibiotic group had an infection rate of 11.1% (9/81) versus 8.3% (8/97) in patients not receiving antibiotics, p = .52. Demographic, tumor, or surgical characteristics were not associated with an increased infection rate, p > .05.
CONCLUSION: There is no decrease in infection rate of below the knee MMS with preoperative prophylactic antibiotics.