Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC · 2026
Safety of Messenger RNA COVID-19 Vaccination During Pregnancy: Findings from Post-Vaccination Follow-Up Data from the Canadian National Vaccine Safety Network.
СтатьяНазвание и аннотация: Перевод в очереди
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Soe Phyumar, Muller Matthew P, Isenor Jennifer E, Valiquette Louis, Vanderkooi Otto G, Kellner James D, Top Karina A, De Serres Gaston, McGeer Allison, Kiely Marilou, Shulha Hennady P, Irvine Michael A, Marty Kimberly, Sadarangani Manish, Bettinger Julie A, Canadian Immunization Research Network
Аннотация
This communication reports post-vaccination follow-up findings from the Canadian National Vaccine Safety Network on COVID-19 vaccination during pregnancy. Among 6606 pregnant participants who received an messenger RNA COVID-19 primary series, 4302 reported their pregnancy status in follow-up surveys. Within 7 months of vaccination, live birth was the most reported outcome, followed by ongoing pregnancy. Our descriptive analysis indicated pregnancy loss among participants vaccinated in the first trimester (8.9%) appeared to be lower than expected and lower than the rates observed both before and during the COVID-19 pandemic. These findings support the safety of messenger RNA COVID-19 vaccination during pregnancy, including early gestation, and current public health recommendations.