Subintimal angioplasty of isolated infragenicular vessels in lower limb ischemia: long-term results.

PURPOSE: To assess the outcome of subintimal angioplasty in treating isolated infragenicular arterial disease in patients with severe lower limb ischemia.

METHODS

A retrospective study reviewed 67 consecutive patients (39 men; mean age 76 years, range 41-96) who underwent infragenicular subintimal angioplasty between March 1997 and May 2000 for ischemia in 70 limbs. The median length of occlusion was 6 cm [corrected] (range 1-10) in the below-knee popliteal arteries, 4 cm [corrected] (range 1-4) in the tibioperoneal trunk, 21 cm [corrected] (range 1-35) in the anterior tibial artery, 10 (1-30) in the posterior tibial artery, and 5 (range 1-20) in the peroneal artery.

RESULTS

The technical and clinical success rates were 86% and 80%, respectively. In the 10 (14%) patients with a technical failure, 3 underwent successful bypass, 4 had an amputation, 1 had a lumbar sympathectomy, and 2 were treated conservatively. Of the 4 (6%) limbs that did not achieve clinical success, 2 patients required femorodistal bypass and their ulcers improved; in the other 2, ulcerations did not heal completely. The cumulative limb salvage rate and freedom from critical limb ischemia (CLI) quantified by Kaplan-Meier life-table analysis were 94% and 84% at 36 months. Mortality rates were 19% at 1 year, 43% at 2 years, and 51% at 3 years. In a subgroup analysis, the rate of CLI was significantly lower in nondiabetics (4%) and than in diabetics (24%, p=0.02), but neither survival nor amputation rates were significantly different.

CONCLUSIONS

Subintimal angioplasty is a safe and effective procedure for treating isolated crural vessels in patients with severe lower limb ischemia.