Progressive arterial thrombosis in a patient with non-Hodgkin's lymphoma, a lupus anticoagulant, factor V Leiden mutation and paraprotein, following chemotherapy.

We report a case of non-Hodgkin's lymphoma (NHL), with a preceding history of sarcoidosis, in a patient with a lupus anticoagulant (LA), a low-level paraprotein and heterozygosity for the factor V Leiden mutation. Following cytotoxic chemotherapy the patient developed a progressive arterial thrombosis necessitating a left below-knee amputation.