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Magnetic resonance imaging · 2025

Evaluation of vascular calcification and Vessel Wall in patients with lower extremity artery disease using CT-like imaging.

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Hatakeyama Hidehisa, Sakai Takayuki, Suzuki Sakuramaru, Murayama Daichi, Itou Hajime, Ochi Shigehiro

Аннотация

PURPOSE: Lower extremity artery disease (LEAD), a major manifestation of peripheral arterial disease (PAD), is significantly influenced by vascular calcification, which impacts treatment outcomes. This study evaluates the feasibility of CT-like imaging using 3D multi-echo T2*-weighted image (T2*WI) for assessing vascular calcifications and vessel wall area in patients with LEAD.

MATERIALS AND METHODS: A 3.0 T MRI system was used to acquire CT-like images from 20 patients with LEAD (median age: 75.0 years). Vascular calcifications were assessed in 10 patients who had previously undergone non-contrast CT, while vessel wall area was evaluated in another 10 patients using three-dimensional (3D) fat-suppressed T1-weighted turbo spin-echo (FS-T1 TSE).

RESULTS: CT-like imaging demonstrated moderate agreement with non-contrast CT for the visual assessment of vascular calcifications (κ = 0.75) and a strong correlation for the quantitative evaluation of calcification (r = 0.91-0.96). Bland-Altman analysis showed minimal bias in vessel wall area measurements between CT-like imaging and FS-T1 TSE.

CONCLUSION: CT-like imaging is a feasible technique for assessing vascular calcifications and vessel wall area in patients with LEAD. The absence of radiation exposure makes it a promising alternative to CT for vascular evaluation.

Предметные рубрики MeSH

ИП Урсолов Владлен Сергеевич

ИНН 500118482352 · ОГРНИП 314500117700049

Реквизиты и контакты