Urology · 1998
Impact of urometabolic evaluation on prevention of urolithiasis: a retrospective study.
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van Drongelen J, Kiemeney L A, Debruyne F M, de la Rosette J J
Аннотация
OBJECTIVES: To obtain information on compliance to therapy and study its effect on recurrences. Over the past 20 years, a selective therapy protocol has been formed for prevention of urolithiasis recurrence. Many studies have been performed on the effectiveness of this therapy, but compliance has never been examined.
METHODS: Data were abstracted from 177 medical records of patients who were seen at the outpatient clinic between 1985 and 1994. At that time, they were advised to follow a specific therapy regimen (high fluid intake, medication, and/or specific diet) on the basis of the outcome of a standardized metabolic evaluation.
RESULTS: Thirty-six percent of the study population was still compliant to the prescribed therapy after a mean period of 5.3 years of follow-up. Therapy-compliant patients were older and had had more treatments, more lithiasis-related complaints, and more frequent follow-up visits. These characteristics suggest that patients' awareness of their disease might improve compliance. Survival analyses showed that patients can be classified into two groups characterized by the frequency of stone formation: a single stone episode versus frequent periods of stone formation. It appeared that the stone recurrence rate was twice as high among patients with a history of frequent stones compared with patients with a single stone episode, even though compliance to therapy seemed lower in the latter group.
CONCLUSIONS: The usefulness of urometabolic evaluation and subsequent therapy advice seems questionable. Compliance to a life-long therapy is very low after a relatively short follow-up period. This study also suggests a prognostic classification based on stone rate.
METHODS: Data were abstracted from 177 medical records of patients who were seen at the outpatient clinic between 1985 and 1994. At that time, they were advised to follow a specific therapy regimen (high fluid intake, medication, and/or specific diet) on the basis of the outcome of a standardized metabolic evaluation.
RESULTS: Thirty-six percent of the study population was still compliant to the prescribed therapy after a mean period of 5.3 years of follow-up. Therapy-compliant patients were older and had had more treatments, more lithiasis-related complaints, and more frequent follow-up visits. These characteristics suggest that patients' awareness of their disease might improve compliance. Survival analyses showed that patients can be classified into two groups characterized by the frequency of stone formation: a single stone episode versus frequent periods of stone formation. It appeared that the stone recurrence rate was twice as high among patients with a history of frequent stones compared with patients with a single stone episode, even though compliance to therapy seemed lower in the latter group.
CONCLUSIONS: The usefulness of urometabolic evaluation and subsequent therapy advice seems questionable. Compliance to a life-long therapy is very low after a relatively short follow-up period. This study also suggests a prognostic classification based on stone rate.