Zhongguo shi yan xue ye xue za zhi · 2026
[Research on Difficult Blood Matching of Anti-"Mur" and Screening of Mur Blood Group Antigens and Anti-"Mur" Antibodies in Guiyang, Guizhou Province].
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Chen Qiang, Chen Dao-Hui, Xiong Lang, An Xiao-Qiong, Re Zhen-Kui, Yang Tian-Wen, Zhong Jiang, Zhang Jie
Аннотация
OBJECTIVE: To analyze a difficult to match blood recipient who tested negative for irregular antibody screening and positive for anti-"Mur" antibodies, and to screen the distribution frequency of Mur blood type antigens and anti-"Mur" antibodies in patients in Guiyang, Guizhou.
METHODS: Blood type serological tests were used to identify the blood type, screen and identify antibodies, determine antibody titers, and perform cross matching on the blood recipient. Mur blood group antigen and anti-"Mur" antibody were screened by microcolumn gel method.
RESULTS: Anti-"Mur" (IgM titer 16, IgG titer 8) was detected in the plasma of the blood recipient. Blood with no agglutination in both the primary and secondary sides was selected. The blood recipient had no adverse reactions after transfusion, indicating effective transfusion. Among patients seeking medical care in the Guiyang area, 46 cases (6.62%, 46/695) were identified as Mur blood group antigen positive, and 4 cases (0.58%, 4/695) were anti-"Mur" antibody positive.
CONCLUSION: Blind matching method can be used to screen for cross matched blood transfusions, but specific antibody identification should be carried in the future. The screening of Mur blood type antigens and anti-"Mur" antibodies has important clinical significance in the Guiyang area. To avoid the missed detection of irregular antibodies, antibody screening cells with positive Mur blood type antigens should be selected for irregular antibody screening.
METHODS: Blood type serological tests were used to identify the blood type, screen and identify antibodies, determine antibody titers, and perform cross matching on the blood recipient. Mur blood group antigen and anti-"Mur" antibody were screened by microcolumn gel method.
RESULTS: Anti-"Mur" (IgM titer 16, IgG titer 8) was detected in the plasma of the blood recipient. Blood with no agglutination in both the primary and secondary sides was selected. The blood recipient had no adverse reactions after transfusion, indicating effective transfusion. Among patients seeking medical care in the Guiyang area, 46 cases (6.62%, 46/695) were identified as Mur blood group antigen positive, and 4 cases (0.58%, 4/695) were anti-"Mur" antibody positive.
CONCLUSION: Blind matching method can be used to screen for cross matched blood transfusions, but specific antibody identification should be carried in the future. The screening of Mur blood type antigens and anti-"Mur" antibodies has important clinical significance in the Guiyang area. To avoid the missed detection of irregular antibodies, antibody screening cells with positive Mur blood type antigens should be selected for irregular antibody screening.