Anthelmintic activity of mebendazole against induced and naturally occurring helminth infections in cats.

A formulation of mebendazole was used to determine the optimal dosage level against induced and/or naturally occurring infections of Toxocara cati, Ancylostoma tubaeforme, and Taenia taeniaeformis in cats. Amounts of 11 mg/kg of body weight/day or 22 mg/kg/day were given for 2, 3, or 4 days. Feces were collected for 7 days and were examined for expelled parasites. Cats were necropsied to recover retained parasites. A regimen of 22 mg/kg/day for 3 days was determined to be optimal with efficacies of 100%, 99%, and 50% against T cati, A tubaeforme, and Taenia taeniaeformis, respectively.