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DOI 10.1093/cid/ciaf680

Медицинская библиотека · Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026

2025 Clinical Practice Guideline Update by the Infectious Diseases Society of America on the Treatment and Management of COVID-19: Antiviral Treatment for Mild to Moderate COVID-19 in Adults.

Shumaker Amy Hirsch, Bhimraj Adarsh, Bedimo Roger, Cheng Vincent Chi-Chung, Chew Kara W, Daar Eric S, Glidden David V, Shafer Robert W, Tien Phyllis C, Baden Lindsey R, Cawcutt Kelly, Chiotos Kathleen, Dzierba Amy L, Hardy Erica J, Johnson Steven, Kim Arthur Y, MacBrayne Christine, Martin Greg S, Nadig Nandita, Nakamura Mari M, Oliveira Carlos R, Pearson Jeffrey C, Riley Laura, Shoham Shmuel, Tebas Pablo, Willis Zachary, Wolf Joshua, Loveless Jennifer, Morgan Rebecca L, Falck-Ytter Yngve, Gandhi Rajesh T

СтатьяКлинические рекомендацииПоддержка NIH: внешняя программаПеревод пока не подготовлен

Аннотация

This article provides a focused update to the clinical practice guideline on the treatment and management of people with COVID-19, developed by the Infectious Diseases Society of America. The guideline panel presents 9 updated recommendations on the use of nirmatrelvir/ritonavir, remdesivir, and molnupiravir, in adults with mild to moderate COVID-19. The recommendations are based on evidence derived from a systematic literature review and adhere to a standardized methodology for rating the certainty of evidence and strength of recommendation according to the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) approach. The panel also provides a section on how to apply these recommendations, including an algorithm on the selection of antivirals.

Для цитирования: Shumaker Amy Hirsch, Bhimraj Adarsh, Bedimo Roger, Cheng Vincent Chi-Chung, Chew Kara W, Daar Eric S, Glidden David V, Shafer Robert W, Tien Phyllis C, Baden Lindsey R, Cawcutt Kelly, Chiotos Kathleen, Dzierba Amy L, Hardy Erica J, Johnson Steven, Kim Arthur Y, MacBrayne Christine, Martin Greg S, Nadig Nandita, Nakamura Mari M, Oliveira Carlos R, Pearson Jeffrey C, Riley Laura, Shoham Shmuel, Tebas Pablo, Willis Zachary, Wolf Joshua, Loveless Jennifer, Morgan Rebecca L, Falck-Ytter Yngve, Gandhi Rajesh T. 2025 Clinical Practice Guideline Update by the Infectious Diseases Society of America on the Treatment and Management of COVID-19: Antiviral Treatment for Mild to Moderate COVID-19 in Adults.. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2026. DOI: 10.1093/cid/ciaf680.

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