Endokrynologia Polska · 2010
Effect of individual and socio-economic risk factors on the incidence of thyroid carcinoma in Olsztyn province.
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Bandurska-Stankiewicz Elżbieta, Aksamit-Białoszewska Ewa, Rutkowska Joanna, Stankiewicz Aleksander, Shafie Danuta
Аннотация
INTRODUCTION: The aim of this study was an investigation into the individual and socio-economic risk factors of the incidence of thyroid carcinoma.
MATERIAL AND METHODS: Our study was into risk factors affecting the incidence of thyroid carcinoma conducted in patients included in a register of thyroid carcinoma. For that purpose, a questionnaire was prepared which covered personal information, medical history and socio-economic factors. A statistical analysis was conducted.
RESULTS: The register comprised 297 patients (89% female) with thyroid carcinoma and 589 healthy subjects. Age group distribution was similar for both groups. The largest group was aged 50-54. The number of children born to women with carcinoma and women in the control group did not differ significantly. 10% of the women with carcinoma had used contraception. Patients were most frequently born in Olsztyn province, an area of relative iodine deficiency. 9.72% had suffered from thyroid disease in childhood. 32.41% had a family history of thyroid disease. Mothers of patients most frequently also came from regions of similar iodine level. The fathers most frequently came from Warsaw province (17.08%). The origin of the remainder was the same as of the mothers. 36% of patients had elementary, 14% vocational, 38% secondary and 13% higher education. Logistic regression showed that the risk of carcinoma increased 0.98 times in each person younger by a year. Individuals with body mass lower had 0.98 times greater risk of the disease by each kilogram.
CONCLUSIONS: The risk factors for the incidence of thyroid carcinoma: female sex, age at onset, low body mass.
MATERIAL AND METHODS: Our study was into risk factors affecting the incidence of thyroid carcinoma conducted in patients included in a register of thyroid carcinoma. For that purpose, a questionnaire was prepared which covered personal information, medical history and socio-economic factors. A statistical analysis was conducted.
RESULTS: The register comprised 297 patients (89% female) with thyroid carcinoma and 589 healthy subjects. Age group distribution was similar for both groups. The largest group was aged 50-54. The number of children born to women with carcinoma and women in the control group did not differ significantly. 10% of the women with carcinoma had used contraception. Patients were most frequently born in Olsztyn province, an area of relative iodine deficiency. 9.72% had suffered from thyroid disease in childhood. 32.41% had a family history of thyroid disease. Mothers of patients most frequently also came from regions of similar iodine level. The fathers most frequently came from Warsaw province (17.08%). The origin of the remainder was the same as of the mothers. 36% of patients had elementary, 14% vocational, 38% secondary and 13% higher education. Logistic regression showed that the risk of carcinoma increased 0.98 times in each person younger by a year. Individuals with body mass lower had 0.98 times greater risk of the disease by each kilogram.
CONCLUSIONS: The risk factors for the incidence of thyroid carcinoma: female sex, age at onset, low body mass.