Procedural Techniques, Airway Management, and Specimen Acquisition for Peripheral Lung Transbronchial and Endobronchial Ultrasound-Guided Cryobiopsy: A Modified Delphi Consensus Statement.
Обработка статьи · этапы, ошибки и управление
Ошибки и ограничения
История · было → стало
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Beattie Jason A, Kapp Christopher M, Thiboutot Jeffrey, Aboudara Matthew C, Akulian Jason, Argento A Christine, Casal Roberto F, Cheng George, De Cardenas Jose, DeMaio Andrew, Diez-Ferrer Marta, Fan Ye, Gonzales Anne V, Herth Felix, Husta Bryan, Ji Wonjun, Kagima Jacqueline Wanjiku, Keyes Colleen, Kim Yeon Wook, Liberman Moishe, Majid Adnan, Navani Neal, Oberg Catherine L, Poletti Venerino, Seides Benjamin J, Silvestri Gerard, Wahidi Momen, Yu Diana H, Maldonado Fabien, Feller-Kopman David, Yarmus Lonny B, Gilbert Christopher R, Interventional Pulmonary Outcomes Group
Аннотация
RESEARCH QUESTION: What are areas of clinical consensus regarding indications, tools, techniques, specimen handling, safety considerations, and requisite procedural expertise for the use of the 1.1 mm cryoprobe in non-interstitial lung disease transbronchial cryobiopsy, including convex-probe endobronchial ultrasound-guided and peripheral pulmonary lesion sampling?
STUDY DESIGN AND METHODS: An international panel of bronchoscopy experts was assembled through the Interventional Pulmonology Outcomes Group. Following a structured evidence review, a modified Delphi methodology was conducted, consisting of an initial round of open-ended questions followed by 3 rounds in which panelists rated their agreement with statements on a 5-point Likert scale. Consensus was defined a priori as ≥ 80% agreement. Domains included: (1) peripheral transbronchial cryobiopsy, (2) convex-probe endobronchial ultrasound-guided cryobiopsy, (3) airway, anesthesia, and complication management, and (4) specimen handling and processing.
RESULTS: A total of 32 physicians participated in this project. The modified Delphi process consisted of 4 survey rounds conducted between May and November 2025. Consensus was obtained on 31 statements. No consensus was obtained on 17 statements.
INTERPRETATION: To our knowledge, this Delphi statement represents the first expert guidance for non-interstitial lung disease applications of both endobronchial ultrasound-guided and peripheral transbronchial cryobiopsy. The consensus statements delineate contemporary best practices, bridge critical gaps in standardization, and outline domains where further research is needed.