Endoscopic Closure Techniques in Third-space Endoscopy.

Although third-space endoscopic procedures, such as peroral endoscopic myotomy, have garnered increasing interest for the management of esophageal and gastric motility and obstructive disorders, there remains no consensus on the optimal method for closure of the mucosal incision site. This article aims to compare various endoscopic closure techniques utilized in third-space endoscopy, including through-the-scope (TTS) clips, over-the-scope (OTS) clips, and TTS and OTS endoscopic suturing.