Long-term survival after resection of a hepatocellular carcinoma with lymph node metastasis and discontinuation of oral contraceptives.

The occurrence of a hepatocellular carcinoma is described in a young woman who had been taking oral contraceptives for 2 1/2 years. She was treated by wedge excision of the tumor. At the time of operation, lymph node metastasis was present. After the operation oral contraceptives were discontinued. No evidence of residual or recurrent tumor could be demonstrated during a follow-up period of 6 years. This is the first report on long-term survival after nonradical resection of metastasized hepatocellular carcinoma associated with the use of birth control pills.