European heart journal open · 2026
Comparison between no fasting vs. fasting in patients undergoing cardiac catheterization laboratory procedures: a systematic review and meta-analysis.
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Segura-Saldaña Pedro, Alvarez-Vargas Mayita, Ludeña-Meléndez Victor, Llaja-Socorro Juan, Davila-Paredes Carlos, Sánchez-Cárdenas José, Galvez-Rodriguez Estefani, Santillán-Rodríguez Arón, Cabrera-Cruzado Carlos, Guerra-Canchari Pedro, Diaz-Arocutipa Carlos
Аннотация
AIMS: Fasting prior to procedures in the cardiac catheterization laboratory is an established indication in clinical practice. However, the evidence supporting this recommendation is uncertain.
OBJECTIVES: The aim of this systematic review and meta-analysis was to evaluate the impact of non-fasting vs. fasting before cardiac catheterization.
METHODS AND RESULTS: PubMed, Embase, Scopus, and Web of Science databases were searched until September 2024. Randomized controlled trials comparing both strategies were included. Outcomes were hypoglycaemia, aspiration pneumonia, contrast-induced acute kidney injury (AKI), nausea/vomiting, hypotension, and patient satisfaction. Risk of bias was assessed using the RoB 2.0 tool. All meta-analyses were performed using a random-effects model. Six studies were included (n = 2736). The mean age ranged from 62 to 70 years, and 31% were female. There was no significant difference in the risk of hypoglycaemia [risk ratio (RR) 0.82, 95% confidence interval (CI) 0.49-1.38], aspiration pneumonia (RR 1.31, 95% CI 0.28-6.05), nausea/vomiting (RR 0.95, 95% CI 0.58-1.55), contrast-induced AKI (RR 1.87, 95% CI 0.94-3.72) between the non-fasting and fasting groups. In contrast, patients in the non-fasting group had a lower risk of hypotension (RR 0.57, 95% CI 0.38-0.86) and higher satisfaction scores (standardized mean difference -1.53, 95% CI -2.11 to -0.96) compared with the fasting group. The risk of bias was judged as some concerns in three of four studies.
CONCLUSION: Our results suggest that in patients who underwent cardiac catheterization procedures, non-fasting was a safe strategy and provoked higher satisfaction compared to fasting.
OBJECTIVES: The aim of this systematic review and meta-analysis was to evaluate the impact of non-fasting vs. fasting before cardiac catheterization.
METHODS AND RESULTS: PubMed, Embase, Scopus, and Web of Science databases were searched until September 2024. Randomized controlled trials comparing both strategies were included. Outcomes were hypoglycaemia, aspiration pneumonia, contrast-induced acute kidney injury (AKI), nausea/vomiting, hypotension, and patient satisfaction. Risk of bias was assessed using the RoB 2.0 tool. All meta-analyses were performed using a random-effects model. Six studies were included (n = 2736). The mean age ranged from 62 to 70 years, and 31% were female. There was no significant difference in the risk of hypoglycaemia [risk ratio (RR) 0.82, 95% confidence interval (CI) 0.49-1.38], aspiration pneumonia (RR 1.31, 95% CI 0.28-6.05), nausea/vomiting (RR 0.95, 95% CI 0.58-1.55), contrast-induced AKI (RR 1.87, 95% CI 0.94-3.72) between the non-fasting and fasting groups. In contrast, patients in the non-fasting group had a lower risk of hypotension (RR 0.57, 95% CI 0.38-0.86) and higher satisfaction scores (standardized mean difference -1.53, 95% CI -2.11 to -0.96) compared with the fasting group. The risk of bias was judged as some concerns in three of four studies.
CONCLUSION: Our results suggest that in patients who underwent cardiac catheterization procedures, non-fasting was a safe strategy and provoked higher satisfaction compared to fasting.