Prognostic value of coronary computed tomography angiography in patients with prior percutaneous coronary intervention.

OBJECTIVE

We sought to determine the prognostic value of coronary computed tomography angiography (CCTA) in patients with a history of percutaneous coronary intervention (PCI).

BACKGROUND

Although the prognostic value of CCTA has been well studied, its incremental value in patients with previous PCI has not been robustly investigated.

METHODS

Consecutive patients with previous PCI were prospectively enrolled and CCTA images were evaluated for coronary artery disease (CAD) severity. Patients were followed for major adverse cardiovascular events (MACE) which was a composite of cardiac death and non-fatal myocardial infarction. All-cause death was assessed as a secondary endpoint.

RESULTS

A total of 501 patients were analyzed with a mean follow-up time of 59.5 ± 32.0 months and 52 patients (10.4%) experienced MACE. Multivariable Cox regression analysis showed that CAD severity was a predictor of MACE with 0, 1, 2, and 3 vessel disease having annual rates of 1.3%, 2.2%, 2.2%, and 5.3%, respectively. All-cause death was similar in all categories of CAD.

CONCLUSIONS

In patients with previous PCI, CAD severity as measured with CCTA has independent and incremental prognostic value.