Usefulness of the Slope of the Preload Recruitable Stroke Work Relationship for the Prediction of Rehospitalization After Transcatheter Mitral Edge-to-Edge Repair.

BACKGROUND

Among patients with functional mitral regurgitation (FMR), responders to transcatheter mitral edge-to-edge repair (TEER) remain unclear. We investigated whether the slope of the preload recruitable stroke work relationship (Mw; calculated as stroke work / [EDV - k × EDV + {1 - k} × LV wall], where EDV is end-diastolic volume, k is a constant, and LV wall is the volume of the left ventricular wall) could predict rehospitalization in FMR patients after TEER.

METHODS AND

RESULTS

Mwwas calculated for 24 FMR patients using echocardiography. The median left ventricular ejection fraction was 27% and the median Mwwas 32. Over a 498-day median follow-up period, 38% of patients were rehospitalized for heart failure, and only Mwhad a high area under the curve in time-dependent receiver operating characteristic analysis.

CONCLUSIONS

Mwis an effective predictor for rehospitalization in FMR patients after TEER.