Therapeutic inertia in rhythm control strategies in hospitalized patients with fibrillation: Insights from Hellenic Cardiorenal Morbidity Snapshot (HECMOS) study.
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Vlachakis Panayotis K, Tsiachris Dimitris, Doundoulakis Ioannis, Tsioufis Panagiotis, Kordalis Athanasios, Botis Michail, Leontsinis Ioannis, Antoniou Christos-Konstantinos, Papachrysostomou Chrysostomi, Dimitroula Vasiliki, Maneta Eleni, Chalkitis Vasileios, Kotsakis Theodoros, Skantzikas Pavlos, Kafkas Nikolaos, Sidiropoulos Georgios, Roussos Dimitris, Trikas Athanasios, Koudounis Georgios, Kolettis Theofilos M, Smyrnioudis Nikolaos, Christakos Dimitrios, Chasikidis Christos, Gatzoulis Konstantinos A, Tsioufis Konstantinos
Аннотация
METHODS: HECMOS was a nationwide snapshot survey of cardiorenal morbidity in hospitalized cardiology patients. In this sub-study, we included 276 cases who had a history of AF, particularly on the rhythm strategy, and catheter ablation procedures had been performed before the index admission.
RESULTS: Among 276 AF patients (mean age: 76.4 ± 11.5 years, 58 % male), 60.9 % (N = 168) had persistent AF and 39.1 % (N = 108) had paroxysmal AF. Heart failure was the main cause of admission in 54.3 % (N = 145) of the patients, while 14.1 % (N = 39) were admitted due to paroxysmal AF, 7.3 % (N = 20) due to bradyarrhythmic reasons, and 6.5 % (N = 18) suffered from acute coronary syndrome. Most importantly, heart failure with reduced ejection fraction was present in 76 (27 %) patients. Only 10 patients out of the total (3 %, mean age 59.7 years) had undergone AF ablation while electrical cardioversion had been attempted in 37 (13.4 %) patients. Interestingly, in this AF population with heart failure, 3.6 % (N = 10) had a defibrillator implanted (4 single-chamber), and only 1.5 % (N = 4) had a cardiac resynchronization therapy defibrillator (CRT-D).
CONCLUSION: High prevalence of persistent AF was detected in hospitalized patients, with heart failure being the leading cause of admission and main co-morbidity. Rhythm control strategies are notably underused, along with CRT-D implantation in patients with AF and heart failure.