MMWR. Morbidity and mortality weekly report · 2022
Ocular Monkeypox - United States, July-September 2022.
СтатьяНазвание и аннотация: Перевод в очереди
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Cash-Goldwasser Shama, Labuda Sarah M, McCormick David W, Rao Agam K, McCollum Andrea M, Petersen Brett W, Chodosh James, Brown Catherine M, Chan-Colenbrander Suk Yin, Dugdale Caitlin M, Fischer Michael, Forrester Amy, Griffith Jayne, Harold Rachel, Furness Bruce W, Huang Vivian, Kaufman Aaron R, Kitchell Ellen, Lee Rachel, Lehnertz Nicholas, Lynfield Ruth, Marsh Ketzela Jacobowitz, Madoff Lawrence C, Nicolasora Nelson, Patel Dharmendra, Pineda Roberto, Powrzanas Trey, Roberts Afsoon, Seville Maria Teresa, Shah Ami, Wong Joshua M, Ritter Jana M, Schrodt Caroline A, Raizes Elliot, Morris Sapna Bamrah, Gold Jeremy A W, CDC Monkeypox Clinical Escalations Team
Аннотация
As of October 11, 2022, a total of 26,577 monkeypox cases had been reported in the United States.* Although most cases of monkeypox are self-limited, lesions that involve anatomically vulnerable sites can cause complications. Ocular monkeypox can occur when Monkeypox virus (MPXV) is introduced into the eye (e.g., from autoinoculation), potentially causing conjunctivitis, blepharitis, keratitis, and loss of vision (1). This report describes five patients who acquired ocular monkeypox during July-September 2022. All patients received treatment with tecovirimat (Tpoxx)†; four also received topical trifluridine (Viroptic).§ Two patients had HIV-associated immunocompromise and experienced delays between clinical presentation with monkeypox and initiation of monkeypox-directed treatment. Four patients were hospitalized, and one experienced marked vision impairment. To decrease the risk for autoinoculation, persons with monkeypox should be advised to practice hand hygiene and to avoid touching their eyes, which includes refraining from using contact lenses (2). Health care providers and public health practitioners should be aware that ocular monkeypox, although rare, is a sight-threatening condition. Patients with signs and symptoms compatible with ocular monkeypox should be considered for urgent ophthalmologic evaluation and initiation of monkeypox-directed treatment. Public health officials should be promptly notified of cases of ocular monkeypox. Increased clinician awareness of ocular monkeypox and of approaches to prevention, diagnosis, and treatment might reduce associated morbidity.