Transplant infectious disease : an official journal of the Transplantation Society · 2025
Measles and Solid Organ Transplantation: Diagnosis, Treatment, and Prevention.
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Pouch Stephanie M, Ravindra Akshatha, Dong Sara W, Clemente Wanessa Trindade, La Hoz Ricardo M, Mishkin Aaron, Hand Jonathan, Freire Maristela Pinheiro, Simkins Jacques, Wolfe Cameron, Baddley John W
Аннотация
The recent international resurgence of measles has led to significant public health concerns and poses significant risks to immunocompromised patients, including those who have undergone solid organ transplantation (SOT). SOT recipients may present atypically and are at an increased risk of severe complications of measles infection, underscoring the importance of preventative measures. This review summarizes contemporary data regarding measles transmission, the clinical presentation, diagnosis, and treatment of SOT recipients, as well as strategies for measles prevention, infection control considerations, postexposure prophylaxis, and opportunities for the mitigation of donor-derived measles and measles vaccine viruses.