MEASLES IN PREGNANCY IN THE REPUBLIC OF KAZAKHSTAN: CLINICAL AND LABORATORY MANIFESTATIONS AND OUTCOMES.

PURPOSE: to study clinical and laboratory manifestations of measles in pregnant women, prognosis and outcomes of the disease in Kazakhstan (January 2023 - February 2024).

METHODS

334 medical records of women (20-43 years old) with confirmed diagnosis of measles (ELISA) were analyzed. General, biochemical blood tests and inflammatory markers were investigated.

RESULTS

- 20% of pregnant women were treated as inpatients and the rest as outpatients. - A spike in hospitalizations was recorded during winter months. - Low immunization: 48% of pregnant were unvaccinated and 52% had unknown vaccination status. - Complications included marked intoxication, bacterial infections and perinatal disorders (miscarriages, premature births, fetal deaths).

CONCLUSIONS

Low vaccination rates and increased morbidity increase the risk of severe measles in pregnant women. Pre-pregnancy vaccination remains the only effective prevention method for mother and child.