Frontline gastroenterology · 2011
Colorectal cancer detection: time to abandon barium enema?
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Shariff M K, Sheikh K, Carroll N R, Whitley S, Greenberg D, Parkes M, Cameron E A B
Аннотация
OBJECTIVES: To assess the sensitivity of double contrast barium enema (DCBE) for diagnosing colorectal cancer (CRC).
DESIGN: Retrospective evaluation of DCBE performed in the 2 years prior to diagnosis of CRC.
SETTING: Teaching hospital in Cambridge, UK.
PATIENTS: 1310 consecutive cases of CRC identified from cancer registry data.
INTERVENTIONS: DCBE and colonoscopy.
MAIN OUTCOME MEASURES: Sensitivity of DCBE for diagnosing CRC.
RESULTS: 215 patients had undergone a DCBE within the 2 years prior to diagnosis with CRC. After excluding those reported as inadequate, 37 of these were reported as normal, giving a sensitivity of 83% (81-85%).
CONCLUSIONS: The performance of DCBE is inadequate for the exclusion of CRC. Expansion of colonoscopy and CT colonography capacity is urgently required nationally so that DCBE can finally be abandoned as a firstline test in patients at risk of CRC.
DESIGN: Retrospective evaluation of DCBE performed in the 2 years prior to diagnosis of CRC.
SETTING: Teaching hospital in Cambridge, UK.
PATIENTS: 1310 consecutive cases of CRC identified from cancer registry data.
INTERVENTIONS: DCBE and colonoscopy.
MAIN OUTCOME MEASURES: Sensitivity of DCBE for diagnosing CRC.
RESULTS: 215 patients had undergone a DCBE within the 2 years prior to diagnosis with CRC. After excluding those reported as inadequate, 37 of these were reported as normal, giving a sensitivity of 83% (81-85%).
CONCLUSIONS: The performance of DCBE is inadequate for the exclusion of CRC. Expansion of colonoscopy and CT colonography capacity is urgently required nationally so that DCBE can finally be abandoned as a firstline test in patients at risk of CRC.