Colorectal cancer detection: time to abandon barium enema?

OBJECTIVES

To assess the sensitivity of double contrast barium enema (DCBE) for diagnosing colorectal cancer (CRC).

DESIGN

Retrospective evaluation of DCBE performed in the 2 years prior to diagnosis of CRC.

SETTING

Teaching hospital in Cambridge, UK.

PATIENTS: 1310 consecutive cases of CRC identified from cancer registry data.

INTERVENTIONS: DCBE and colonoscopy.

MAIN OUTCOME MEASURES: Sensitivity of DCBE for diagnosing CRC.

RESULTS

215 patients had undergone a DCBE within the 2 years prior to diagnosis with CRC. After excluding those reported as inadequate, 37 of these were reported as normal, giving a sensitivity of 83% (81-85%).

CONCLUSIONS

The performance of DCBE is inadequate for the exclusion of CRC. Expansion of colonoscopy and CT colonography capacity is urgently required nationally so that DCBE can finally be abandoned as a firstline test in patients at risk of CRC.