[Observation on curative effect of chronic ulcerative colitis treated by retention enema with combination of Chinese and Western drugs].

OBJECTIVE

To evaluate the effect of retention enema with combination of Chinese and Western drugs in treating chronic ulcerative colitis (CUC).

METHODS

The therapeutic effects of retention enema with combination of Chinese and Western drugs (as tested group) and with Western drugs alone (as control group) were compared in a randomized controlled trial.

RESULTS

The total effective rate of clinical curative in the tested group and the control group was 96.7% and 73.3% respectively, the difference between them was significant (chi2 = 4.71, P < 0.05). Statistical difference in comparing pre- and post-treatment condition and comparing between groups was shown in comparison of symptoms, scores of endoscopic picture (except that of polypus), and routine examination of stool (except pus cell number, all P < 0.05). The total recurrence rate of the tested group was 33.3% and the control group 60.0%, the difference between them was significant (chi2 = 4.286, P < 0.05).

CONCLUSION

Retention enema with combination of Chinese and Western drugs has good curative effects in treating CUC.