Relationships among premorbid alcohol use, acute intoxication, and early functional status after traumatic brain injury.

OBJECTIVE

To investigate the relationships among intoxication at time of injury, preinjury history of problem drinking, and early functional status in patients with traumatic brain injury (TBI).

DESIGN

Prospective cohort study.

SETTING

Acute inpatient TBI rehabilitation.

PARTICIPANTS

Participants were 1748 persons with TBI.

INTERVENTIONS: Not applicable.

MAIN OUTCOME MEASURES: Blood alcohol levels (BALs) were obtained at admission to the emergency department, and a history of problem drinking was obtained through interview. Study outcomes, Disability Rating Scale (DRS), and FIM instrument scores were gathered at admission to inpatient rehabilitation.

RESULTS

Multivariate regression analysis revealed that BAL and a history of binge drinking were predictive of DRS, but not FIM, scores. A higher BAL was associated with poorer functional status on the DRS. Paradoxically, a history of binge drinking was associated with more intact functional status on the DRS.

CONCLUSIONS

The relationships among intoxication at time of injury, history of problem drinking, and early outcome after TBI were modest. Injury severity had a more significant association with TBI functional status.