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Войти в исследования Severe tricuspid regurgitation: aetiology, patient characteristics, and treatment: a multicentre, prospective registry.
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Kapłon-Cieślicka Agnieszka, Piasecki Adam, Semczuk-Kaczmarek Karolina, Holcman Katarzyna, Szczepara Sylwia, Kopeć Grzegorz, Krawczyk-Ożóg Agata, Rajtar-Salwa Renata, Sorysz Danuta, Kamiński Karol, Knapp Małgorzata, Stelmaszek Sebastian, Królikowska Maria, Furman-Niedziejko Anna, Gackowski Andrzej, Polańska-Szczap Agata, Tuskowska Grażyna, Koziński Marek, Tomaszuk-Kazberuk Anna, Dudzińska Kinga, Muszyński Paweł, Daniłowicz-Szymanowicz Ludmiła, Kaufmann Damian, Szwoch Małgorzata, Uziębło-Życzkowska Beata, Maciorowska Małgorzata, Krzesiński Paweł, Markiewicz Agata, Bartczak-Rutkowska Agnieszka, Grygier Marek, Kijewski Bartosz, Błaszczyk Robert, Kondracki Bartosz, Rudziński Piotr Nikodem, Demkow Marcin, Dębski Mariusz, Tokarek Tomasz, Dykla Dominika, Zeliaś Aleksander, Gałąska Rafał, Fijałkowski Marcin, Niemiec Małgorzata, Mizia-Stec Katarzyna, Kurnicka Katarzyna, Pruszczyk Piotr, Pręgowski Jerzy, Skowroński Jarosław, Bielecka-Dąbrowa Agata, Kupczyńska Karolina, Pędzich Ewa, Ostrowska Ewa, Tomaniak Mariusz, Grabowski Marcin, Scisło Piotr, Rdzanek Adam
Аннотация
METHODS: This was a prospective, observational study of patients with severe TR, conducted in 18 cardiology centres. Consecutive adult patients with severe TR were included, regardless of the presence of TR symptoms and the cause of hospital admission.
RESULTS: A total of 1295 patients with severe TR were enrolled (median age 76 years, 53% women). The most common reason for admission was HF decompensation (40%). Single TR aetiology was identified in 79% patients. The most frequent overlap between aetiologies included secondary ventricular and atrial TR, and was found in 11% of patients. The most common TR aetiology was secondary atrial (37%), followed by secondary ventricular (25%). Primary and CIED-related TR accounted for 10% and 15%, respectively. In 2.4% TR aetiology was not determined. Patients with secondary atrial and CIED-related TR were the oldest (79 and 78 years, respectively), and those with primary TR the youngest (68 years). Patients with CIED-related and secondary ventricular TR were more often hospitalized for HF decompensation, had more advanced HF symptoms, worse left- and right-ventricular function, worse kidney and liver function, and higher in-hospital mortality. Only 40% of patients underwent evaluation by the Heart Team and 21% were qualified for TR interventions.
CONCLUSIONS: In real life, unequivocal identification of TR aetiology remains challenging. Secondary atrial TR is the most common aetiology. There are significant differences in characteristics and outcomes depending on TR aetiology. Too few patients with severe TR undergo evaluation by the Heart Team.