Paediatrics and international child health · 2012
Factors associated with extreme hyperbilirubinaemia in neonates at the University Hospital of the West Indies.
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Trotman H, Henny-Harry C
Аннотация
AIM: To determine factors associated with extreme hyperbilirubinaemia in neonates at the University Hospital of the West Indies.
METHODS: A retrospective review of all neonates with hyperbilirubinaemia requiring medical intervention at the University Hospital of the West Indies between 1 January 2006 and 30 June 2007 was performed. Factors associated with extreme hyperbilirubinaemia were determined using multiple logistic regression models.
RESULTS: A total of 170 neonates fulfilled the inclusion criteria for the study and 15 (9%) of them had extreme hyperbilirubinaemia. The majority (97, 57%) were term infants and 103 (61%) were male. Exclusively breastfed neonates were more likely to have extreme hyperbilirubinaemia (OR 2.6, 95% CI 0.01-0.6). Neonates whose mothers received oxytocin during labour (OR 2.7, 95% CI 0.02-0.3) and those who were G6PD-deficient (OR 2.6, 95% CI 0.01-0.5) were more likely to have extreme hyperbilurubinaemia.
CONCLUSION: Exclusive breastfeeding, oxytocin use in the mother during labour and G6PD deficiency in the infant were found to be factors associated with extreme hyperbilirubinaemia.
METHODS: A retrospective review of all neonates with hyperbilirubinaemia requiring medical intervention at the University Hospital of the West Indies between 1 January 2006 and 30 June 2007 was performed. Factors associated with extreme hyperbilirubinaemia were determined using multiple logistic regression models.
RESULTS: A total of 170 neonates fulfilled the inclusion criteria for the study and 15 (9%) of them had extreme hyperbilirubinaemia. The majority (97, 57%) were term infants and 103 (61%) were male. Exclusively breastfed neonates were more likely to have extreme hyperbilirubinaemia (OR 2.6, 95% CI 0.01-0.6). Neonates whose mothers received oxytocin during labour (OR 2.7, 95% CI 0.02-0.3) and those who were G6PD-deficient (OR 2.6, 95% CI 0.01-0.5) were more likely to have extreme hyperbilurubinaemia.
CONCLUSION: Exclusive breastfeeding, oxytocin use in the mother during labour and G6PD deficiency in the infant were found to be factors associated with extreme hyperbilirubinaemia.