Treatment of acne scars using subcision combined with concentrated growth factors versus subcision monotherapy: a retrospective cohort study.

Subcision is one of the most frequently used surgical options in improving acne scarring. Concentrated growth factors (CGF), with the potential to assist in the repair and regeneration of tissues, have been extended to the field of cosmetic plastic surgery. Here, we investigate the safety and efficacy of combining CGF (the latest generation of platelet concentrates) with subcision as a novel treatment method. Sixty patients with clinically diagnosed acne scars received either subcision combined with CGF (n = 24) or subcision monotherapy (n = 36). Clinical characteristics and treatment outcomes were documented through photographs, questionnaires, and medical records, with side effects recorded. Both groups showed significant scar improvements, but the combination therapy demonstrated superior outcomes in ECCA score reduction compared to subcision treatment alone. Patients in the combination therapy group reported higher satisfaction levels, and side effects were minimal, except for increased ecchymosis and pain levels which resolved within an acceptable recovery time range for the patients. This combination approach efficiently treats severe acne scars without significant safety risks.