[Blast transformation activity of autologous saliva in patients with different clinical forms of chronic bronchitis].

The study of mitogenic effect of autologous saliva in respect to peripheral blood lymphocytes of patients with different clinical forms of chronic tonsillitis (CT) discovered that saliva from all the examinees was highly active as regards blast-cell transformation. The intensity of lymphocyte blast-transformation in the presence of autologous saliva grows with CT transformation from compensated to decompensated form and insignificantly declines in clinical symptoms of autoimmune disease. The saliva mitogenic effect is probably stimulated by the whole complex of biologically active substances which by provoking hypertrophy of the lymphoid tissue contributes to autoimmunization of the body. It is proposed to use lymphocyte blast-transformation with autologous saliva for diagnosis of subclinical autoimmune diseases.