Medicine · 2019
A case report of ocular tuberculosis in a patient with membranous nephropathy.
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Yin Xiaofang, Ge Haibo, Miao Ruifen
Аннотация
RATIONALE: Membranous nephropathy (MN), a chronic kidney disease (CKD), due to hypoproteinemia, malnutrition, anemia, long-term intake of immunosuppressive agents, changes in cellular immune state, and decrease in antimicrobial peptides, is a high risk for Mycobacterium tuberculosis (MTB) infection, which can cause tuberculosis (TB). TB manifests by various clinical symptoms. Ocular symptoms is a rare presentation of TB. Here, we describe a case of ocular tuberculosis in a patient with MN.
PATIENT CONCERNS: A 63-year-old man with membranous nephropathy (MN) history presented with ocular symptoms.
DIAGNOSES: According to the pathological manifestations of ocular tissue biopsy and a positive polymerase chain reaction (PCR) on samples from sputum and bronchoalveolar lavage fluid (BALF), we elicited a diagnosis of disseminated tuberculosis.
INTERVENTION: The patient received antituberculous therapy and immunosuppressive therapy.
OUTCOMES: The clinical manifestations significantly improved.
LESSONS: Clinicians should be aware of the possibility of TB in cases of immunocompromised patients and perform an appropriate diagnostic work-up for TB.
PATIENT CONCERNS: A 63-year-old man with membranous nephropathy (MN) history presented with ocular symptoms.
DIAGNOSES: According to the pathological manifestations of ocular tissue biopsy and a positive polymerase chain reaction (PCR) on samples from sputum and bronchoalveolar lavage fluid (BALF), we elicited a diagnosis of disseminated tuberculosis.
INTERVENTION: The patient received antituberculous therapy and immunosuppressive therapy.
OUTCOMES: The clinical manifestations significantly improved.
LESSONS: Clinicians should be aware of the possibility of TB in cases of immunocompromised patients and perform an appropriate diagnostic work-up for TB.