Internal medicine (Tokyo, Japan) · 2013
Pneumonitis induced by rifampicin: a case report and literature review.
Клинический случайСтатьяОбзорНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
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Koma Yasuko, Goto Keiko, Yoshida Chihiro, Kimura Kengo, Matsumoto Yusuke, Koyama Midori, Nakashima Nariyasu, Masuya Daiki, Matsuoka Hirofumi, Yoshimatsu Harukazu, Suzuki Yujiro
Аннотация
An 84-year-old woman being treated for miliary tuberculosis (TB) with rifampicin (RFP), isoniazid (INH), ethambutol (EB) and corticosteroids suffered from a persistent fever for five months. While tapering the dose of prednisolone, chest computed tomography (CT) revealed diffuse ground glass opacities (GGO) and bronchoalveolar lavage fluid (BALF) showed an increase in lymphocytes. After the anti-TB drugs were discontinued and the dose of the corticosteroids was increased, the CT findings and fever improved considerably. However, readministration of RFP provoked an inflammatory reaction, leading to a diagnosis of RFP-induced pneumonitis. This condition is very rare. This is the first report of RFP-induced pneumonitis occurring during adjunct steroid therapy.