European heart journal. Imaging methods and practice · 2026
Wideband black- and bright-blood late gadolinium enhancement imaging in patients with implantable cardiac devices at 1.5 T for improved visualization and localization of myocardial injury.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Gut Pauline, Cochet Hubert, Caluori Guido, Vlachos Konstantinos, Antiochos Panagiotis, Durand Baptiste, Masi Ambra, Schwitter Juerg, Sacher Frederic, Jaïs Pierre, Stuber Matthias, Bustin Aurélien
Аннотация
AIMS: Late gadolinium enhancement (LGE) imaging in patients with implantable cardiac devices is often degraded by device-related artefacts. Wideband phase-sensitive inversion recovery (PSIR) mitigates these artefacts but suffers from low scar-blood contrast, limiting detection of subendocardial and small focal scars. Therefore, a novel wideband SPOT (Scar-specific imaging with Preserved myOcardial visualizaTion) sequence combining co-registered wideband black- and bright-blood LGE to improve scar-blood contrast and localization, with wideband inversion recovery and wideband T2 preparation for artefact reduction, was implemented at 1.5 T.
METHODS AND RESULTS: Wideband SPOT was compared with wideband PSIR, conventional PSIR, and conventional SPOT in an animal and 18 patients with devices and known myocardial lesions. Patient analyses included qualitative assessment of image quality, artefact severity, diagnostic confidence, and LGE segment detection; quantitative measurements of left ventricular (LV) volume, scar volume, and scar size; agreement analysis between wideband SPOT and wideband PSIR; and reproducibility analysis. In the animal, wideband SPOT reduced device-related artefacts and enabled accurate scar localization consistent with histology. In patients, wideband SPOT and wideband PSIR yielded similar image and artefact reduction (P > 0.05), but wideband SPOT reduced diagnostic uncertainty by 24% (P = 0.080). Inter-observer agreement for qualitative scores was moderate to good [intra-class correlation coefficient (ICC) 0.54-0.83, P < 0.001]. Quantitative LV and scar measurements demonstrated excellent correlation (r > 0.9, P < 0.01) and good-to-excellent reproducibility (ICC 0.85-0.98, P < 0.001) between techniques.
CONCLUSION: Compared with wideband PSIR, wideband SPOT showed a trend towards enhanced scar detection, identifying additional scarred segments while maintaining similar overall scar burden. It also improved inter-observer agreement, preserved anatomical reference, and reduced device artefacts, which may improve diagnostic confidence and risk stratification.
METHODS AND RESULTS: Wideband SPOT was compared with wideband PSIR, conventional PSIR, and conventional SPOT in an animal and 18 patients with devices and known myocardial lesions. Patient analyses included qualitative assessment of image quality, artefact severity, diagnostic confidence, and LGE segment detection; quantitative measurements of left ventricular (LV) volume, scar volume, and scar size; agreement analysis between wideband SPOT and wideband PSIR; and reproducibility analysis. In the animal, wideband SPOT reduced device-related artefacts and enabled accurate scar localization consistent with histology. In patients, wideband SPOT and wideband PSIR yielded similar image and artefact reduction (P > 0.05), but wideband SPOT reduced diagnostic uncertainty by 24% (P = 0.080). Inter-observer agreement for qualitative scores was moderate to good [intra-class correlation coefficient (ICC) 0.54-0.83, P < 0.001]. Quantitative LV and scar measurements demonstrated excellent correlation (r > 0.9, P < 0.01) and good-to-excellent reproducibility (ICC 0.85-0.98, P < 0.001) between techniques.
CONCLUSION: Compared with wideband PSIR, wideband SPOT showed a trend towards enhanced scar detection, identifying additional scarred segments while maintaining similar overall scar burden. It also improved inter-observer agreement, preserved anatomical reference, and reduced device artefacts, which may improve diagnostic confidence and risk stratification.